The fate of Dominaria — and the Multiverse — is set to unravel. The Phyrexians grow ever stronger, as Elesh Norn inches closer to her plan to conquer the Multiverse. The Planeswalkers who gathered to stop the Phyrexians on Dominaria lost — badly. Now, every plane of the Multiverse is in Phyrexian sights with their plan to invade them all.
The only hope that remains is to take them out on their home turf, destroying the Phyrexian's means to Multiverse invasion. The risk that some of the heroes fall to Phyrexians is high, but the stakes for everyone else are even higher. Planeswalkers team up and head down into New Phyrexia to end the threat of invasion once and for all.